Alex PW LEE

Academic qualifications: MD (2015), FACC (2017), FESC (2017), FRCP (2014), FHKAM (Medicine,
2008), FHKCP (2008), ECFMG (2006), MRCP (UK, 2003), MBChB (Hon, CUHK, 2000)

Present academic positions: Professor of Medicine & Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong Director, Echocardiography Laboratory, Prince of Wales Hospital
Director, Laboratory for Cardiac Imaging and 3D Printing, Li Ka Shing Institute of Health Science

Professional society positions: Chair, Hong Kong College of Cardiology Echocardiography Chapter Board member, Asian-Pacific Association of Echocardiography

Selected publications (h-index: 22; Total publications: 252; Sum of times cited: 1,760)
Fan Y, Yang F, Cheung GS, Chan AK, Wang DD, Lam YY, Chow MC, Leong MC, Kam KK, So KC, Tse G, Qiao Z, He B, Kwok KW, Lee AP. Device sizing guided by echocardiography-based three- dimensional printing is associated with superior outcome after percutaneous left atrial appendage occlusion. Journal of the American Society of Echocardiography. 2019;32:708-719.
Tang Z, Fan YT, Wang Y, Jin CN, Kwok KW, Lee AP. Mitral annular and left ventricular dynamics in atrial functional mitral regurgitation: A three-dimensional and speckle-tracking echocardiographic study. Journal of the American Society of Echocardiography. 2019;32:503-513.

Fan S, Chan A, Au S, Leong MCW, Chow M, Fan YT, Wong R, Chan S, Ng SK, Lee AP, Kwok KW. Personalised anaesthesia: Three-dimensional printing of facial prosthetic for facial deformity with difficult airway. British Journal of Anaesthesia. 2018.

Lee AP, Jin CN, Fan Y, Wong RHL, Underwood MJ, Wan S. Functional implication of mitral annular disjunction in mitral valve prolapse: A quantitative dynamic 3D echocardiographic study. JACC. Cardiovascular imaging. 2017;10:1424-1433.

So KC, Fan Y, Sze L, Kwok KW, Chan AK, Cheung GS, Lee AP. Using multimaterial 3-dimensional printing for personalized planning of complex structural heart disease intervention. JACC. Cardiovascular interventions. 2017;10:e97-e98.

Fan Y, Kwok KW, Zhang Y, Cheung GS, Chan AK, Lee AP. Three-dimensional printing for planning occlusion procedure for a double-lobed left atrial appendage. Circulation. Cardiovascular Interventions. 2016;9: e003561.

Jin CN, Salgo IS, Schneider RJ, Kam KKH, Chi WK, So CY, Tang Z, Wan S, Wong R, Underwood M, Lee AP. Using anatomic intelligence to localize mitral valve prolapse on three-dimensional echocardiography. Journal of the American Society of Echocardiography. 2016;29:938-945.

Lee AP, Hsiung MC, Salgo IS, Fang F, Xie JM, Zhang YC, Lin QS, Looi JL, Wan S, Wong RH, Underwood MJ, Sun JP, Yin WH, Wei J, Tsai SK, Yu CM. Quantitative analysis of mitral valve morphology in mitral valve prolapse using real-time three-dimensional echocardiography: Importance of annular saddle- shape in pathogenesis of mitral regurgitation. Circulation 2013;127:832-41.

Lee AP, Zhang Q, Yip G, Fang F, Liang YJ, Xie JM, Lam YY, Yu CM. Left ventricular mechanical dyssynchrony in heart failure with preserved ejection fraction complicating acute coronary syndrome. JACC: Cardiovasc Imaging. 2011;4:348-57.

Lee AP, Song JK, Yip GW, Zhang Q, Zhu TG, Li C, Chan A, Yu CM. Importance of dynamic dyssynchrony in the occurrence of hypertensive heart failure with normal ejection fraction. Eur Heart J. 2010;31:2642-9.

Lee AP, Lam YY, Yip GW, Lang RM, Zhang Q, Yu CM. Role of real time three-dimensional transesophageal echocardiography in guidance of interventional procedures in cardiology. Heart. 2010;96:1485-93.

Lee AP, Acker M, Kubo SH, Bolling SF, Park SW, Bruce CJ, Oh JK. Mechanisms of recurrent functional mitral regurgitation after mitral valve repair in nonischemic dilated cardiomyopathy: importance of distal anterior leaflet tethering. Circulation. 2009;119:2606-14.

Selected grant record as PI:
Sanofi-Aventis Hong Kong Ltd Research Grant (1/9/2017 – 31/10/2020) Title: Prevalence of Fabry Disease Among Chinese Patients With Left Ventricular Hypertrophy in Hong Kong

HMRF (2017/18) MD17542 Title: 3D Printing Technology for Planning Left Atrial Appendage Occlusion: A Randomised Trial
Innovation and Technology Support Program Tier 3/Seed project (ITS/025/16) Title: Development of 3D-printed Cardiovascular Models for Personalised Structural Intervention.

GRF 2012/2013 (467812) Title: Mitral leaflet adaptation in ischemic functional regurgitation: A prospective clinical study using real-time 3-dimensional echocardiography.

Selected prizes and awards:
The Hong Kong College of Physicians Distinguished Young Fellow 2016 The Hong Kong College of Physicians Richard Yu Lectureship 2015 First class Award of Ministry of Education, China, 2011

The Hong Kong College of Physicians Distinguished Research Paper Award for Young Investigator, 2009, 2011, 2013

European Society of Cardiology EuroEcho-Imaging Young Investigator Award, 2008.