Dr YEUNG Ming Yee Trevor    
楊明義

Assistant Professor
MA (Cantab), MBBChir (Cantab), DPhil (Oxon), FRCS (Eng)

Colorectal Surgery
(852) 3505 1495
trevoryeungadd this for spam@add this for spamsurgery.cuhk.edu.hk
LJL-4719-2024
0000-0002-3108-2649

Biography

Dr Trevor Yeung is Assistant Professor of Colorectal Surgery at Prince of Wales Hospital, The Chinese University of Hong Kong. He is a specialist in robotic colorectal surgery and is fully certified on the Da Vinci robotic platform. He has expertise in "watch and wait" and organ preservation for patients with rectal cancer. His research interests are robotic colorectal surgery, organ preservation for rectal cancer, and investigating how fluorescence imaging can help guide intraoperative decision making and improve surgical and oncological outcomes for patients.

He graduated from medical school at Clare College, Cambridge, UK with triple First Class honours and triple distinctions in Surgery, Obstetrics and Gynaecology and Pathology (top of year) and won numerous prizes including the Clare College Foundation Scholarship, the George Graham Prize and the William Butler Prize for Medical Sciences. He completed his internship and basic surgical training in Cambridge. He was awarded a Cancer Research UK Clinical Research Fellowship and the Sir Alan Parks Research Fellowship from the Royal College of Surgeons of England and obtained a DPhil from Green Templeton College, Oxford, UK for his research on Colorectal Cancer Stem Cells. This was followed by a post-doctoral fellowship at Stanford University, USA. He was appointed Academic Clinical Lecturer at the University of Oxford in 2011 and completed his higher general and colorectal surgical training in Oxford, UK, obtaining his FRCS in 2018. He then completed two dedicated robotic colorectal cancer surgical fellowships at two prestigious international cancer centers - Peter MacCallum Cancer Center, Melbourne, Australia and Memorial Sloan Kettering Cancer Center, New York, USA, where he developed his expertise on robotic surgery and "watch and wait" for rectal cancer.

At Oxford, he developed a strong track record in translational research. He won the prestigious Harry E Bacon Foundation Award at the American Society of Colon and Rectal Surgeons (ASCRS) annual meeting in 2013 and the Best Higher Surgical Trainee Presentation at the Oxford Surgical Symposium 2015 for his work on fluorescence imaging. He was awarded the British Association of Surgical Oncology (BASO) Ronald Raven Travelling Fellowship in 2022 and the Royal College of Surgeons of England Ethicon Foundation Travel Grant in 2023 which supported his robotic colorectal fellowship at Memorial Sloan Kettering Cancer Center.

Research Interests

• Robotic colorectal surgery
• Intraoperative fluorescence Imaging - improving intraoperative decision making during colorectal surgery and improving patient outcomes
• "Watch and wait" for rectal cancer – organ preservation in the setting of patients who develop complete clinical response following total neoadjuvant therapy

Additional Information

Awards and Honours:

Academic

• Clare College Scholarship, University of Cambridge (1999)
• George Graham Prize (1999) - for exceptional academic achievement in MVST Part IA
• Clare College Foundation Scholarship, University of Cambridge (2000)
• William Butler Prize for Medical Sciences, University of Cambridge (2001) - for outstanding results and contribution to College
• PPP Healthcare Award, University of Cambridge (2001) - for exceptional academic merit and outstanding general contribution
• Clare College Prize, University of Cambridge (2003) – for gaining distinctions in Final MB Pathology (top of year) and Final MB Obstetrics and Gynaecology
• Clare College Prize, University of Cambridge (2004) - for gaining distinction in Final MB Surgery
• Domus Merit Award, Green College, University of Oxford (2007) – to recognise and encourage the merit of new students equipped to make an outstanding contribution to College and University life
• Ronald Raven Travelling Fellowship, British Association of Surgical Oncology (BASO) (2022) – to support robotic colorectal fellowship at Memorial Sloan Kettering Cancer Center
• Royal College of Surgeons of England Ethicon Foundation Fund Travel Grant (2023) – to support robotic colorectal fellowship at Memorial Sloan Kettering Cancer Center

Research

• Cancer Research UK Clinical Research Fellowship, University of Oxford (2007)
• Research Fellowship, Royal College of Surgeons of England (2008)
• Sir Alan Parks Research Fellowship, Royal College of Surgeons of England (2009)
• Academy of Medical Sciences Clinical Lecturer Starter Grant (2012)
• Bowel Disease Research Foundation (BDRF) Project Grant (2012)
• Harry E. Bacon Foundation Award (2013) - Best Basic Scientific Podium Presentation, American Society of Colon and Rectal Surgeons (ASCRS) annual meeting, Phoenix, USA
• Goodger Scholarship, University of Oxford (2014) - awarded to assist research into the causes and prevention of disease in its early stages
• Best Higher Surgical Trainee Presentation, Inaugural Oxford Surgical Symposium (2015)

Selected Publications

1. Yeung TM, Larkins KM, Warrier SK, Heriot AG. The Rise of Robotic Colorectal Surgery – Better for Patients and Better for Surgeons. J Robot Surg. 2024 Feb 8;18(1):69. doi: 10.1007/s11701-024-01822-z
2. Hawke JA, Apte SS, Yeung TM, Pham T, Guerra G, Heriot AG, Warrier SK. Open pelvic sidewall excision utilizing an extended lateral plane with excision of the sciatic nerve and ischial spine for recurrent rectal cancer. ANZ J Surg. 2023 Jun;93(6):1704-1706. doi: 10.1111/ans.18304. Epub 2023 Jan 31
3. Sreedharan S, Pham T, Yeung TM, Apte SS, Sivakumar J, Heriot AG, Warrier SK. Intraoperative fluorescence imaging using indocyanine green to assess the lymphatic drainage of a small bowel adenocarcinoma. ANZ J Surg. 2023 Mar;93(3):727-729. doi: 10.1111/ans.17934. Epub 2022 Aug 1.
4. Ishizawa T, McCulloch P, Stassen L, van den Bos J, Regimbeau J, Dembinksi J, Schneider-Koriath S, Boni L, Aoki T, Nishino H, Hasegawa K, Sekine Y, Chen-Yoshikawa T, Yeung T, Berber E, Kahramangil B, Bouvet M, Diana M, Kokudo N, Dip F, White K, Rosenthal R. Assessing the development status of intraoperative fluorescence imaging for anatomy visualization, using the IDEAL framework. BMJ Surg Interv Health Technol. 2022 Nov 4;4(1):e000156. doi: 10.1136/bmjsit-2022-000156
5. Yeung TM, Apte SS, Behrenbruch CC, Warrier SK, Heriot AG. Fluorescent Imaging in Colorectal Surgery – An essential component of care? ANZ J Surg. 2022 Jul;92(7-8):1600-1601. doi: 10.1111/ans.17790
6. Yeung TM. Fluorescence Imaging in Colorectal Surgery. Surg Endosc. 2021 Sep;35(9):4956-4963. doi: 10.1007/s00464-021-08534-7
7. Barnes TG, Hompes R, Birks J, Mortensen NJ, Jones O, Lindsey I, Guy R, George B, Cunningham C, Yeung TM. Methylene blue fluorescence of the ureter during colorectal surgery. Surg Endosc. 2018 Sep;32(9):4036-4043. doi: 10.1007/s00464-018-6219-8. Epub 2018 May 21
8. Yeung TM, Wang LM, Colling R, Kraus R, Cahill R, Hompes R, Mortensen NJ. Intraoperative identification and analysis of lymph nodes at laparoscopic colorectal cancer surgery using fluorescence imaging combined with rapid OSNA pathological assessment. Surg Endosc. 2018 Feb;32(2):1073-1076. doi: 10.1007/s00464-017-5644-4. Epub 2017 Jun 22
9. Colling R, Yeung T, Hompes R, Kraus R, Cahill R, Mortensen N, Wang LM. OSNA testing for lymph node staging in colorectal cancer. J Clin Pathol. 2017 Jul;70(7):638-639. doi: 10.1136/jclinpath-2016-204299. Epub 2017 Mar 27
10. Yeung TM, Volpi D, Tullis IDC, Nicholson G, Buchs N, Cunningham C, Guy R, Lindsey I, George B, Jones O, Wang LM, Hompes R, Vojnovic B, Hamdy F and Mortensen NJ. Identifying ureters in situ under fluorescence during laparoscopic and open colorectal surgery. Ann Surg. 2016 Jan;263(1):e1-2.
11. Li X, Nadauld L, Ootani A, Corney DC, Reetesh KP, Gevaert O, Cantrell MA, Rack PG, Neal JT, Chan CW, Yeung T, Gong X, Yuan J, Wihelmy J, Robine S, Attardi LD, Plevritis SK, Hung KE, Chen CZ, Ji HP, Kuo CJ. Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture. Nat Med. 2014 Jul;20(7):769-77
12. Ashley N, Yeung T, Bodmer WF. Stem Cell Differentiation and Lumen Formation in Colorectal Cancer Cell Lines and Primary Tumours. Cancer Res. 2013 Sep 15;73(18):5798-809.
13. Yeung TM, Buskens C, Wang LM, Mortensen NJ, Bodmer WF. Myofibroblast activation in colorectal cancer lymph node metastases. Br J Cancer. 2013 May 28;108(10):2106-15
14. Yeung TM, Chia LA, Kosinski CM, Kuo CJ. Regulation of self-renewal and differentiation by the intestinal stem cell niche. Cell Mol Life Sci. 2011 Aug;68(15):2513-23
15. Yeung TM, Mortensen NJ. Advances in endoscopic visualisation of colorectal polyps. Colorectal Dis. 2011 Apr;13(4):352-9
16. Yeung TM, Gandhi SC and Bodmer WF. Hypoxia and lineage specification of cell line derived colorectal cancer stem cells. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4382-7
17. Yeung TM, Gandhi SC, Wilding JL, Muschel R and Bodmer WF. Cancer stem cells from colorectal cancer derived cell lines. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3722-7.
18. Yeung TM, Mortensen NJ. Colorectal cancer stem cells. Dis Colon Rectum. 2009 Oct;52(10):1788-1796